A practical reference for drug discovery
Practical explanations of microplate assays, detection technology and the results you see at the bench. Explore assay choices, learn how measurements work, and find insight into controls, variability and experimental conditions.
Choose a microplate assay for the biological event you want to measure, then work through its detection chemistry, controls and interpretation.
Explore what microplate assay signals reveal about your experiment, from background and variability to plate handling and detection effects.
Understand how microplate readers measure light and how detector response, photon statistics and ratio calculations shape the numbers you report.
Compare assay formats and screening equipment by the measurement you need, the controls it requires and the practical trade-offs.
When bright controls look unusually consistent, detector compression may be improving the statistic while distorting the result. Here’s how to tell.
Assay troubleshooting, detection strategy and instrument selection. For now, we’re sharing the knowledge through this library.
Meet Andrew Stewart →